Annals of Maxillofacial Surgery

ORIGINAL ARTICLE - EVALUATIVE STUDY
Year
: 2019  |  Volume : 9  |  Issue : 1  |  Page : 37--47

Management of central giant cell granulomas of the jaws: An unusual case report with critical appraisal of existing literature


Priya Jeyaraj 
 Military Dental Centre (Gough Lines), Secunderabad, Telangana, India

Correspondence Address:
Dr. Priya Jeyaraj
Commanding Officer, Military Dental Centre (Gough Lines), Secunderabad, Telangana, Pin-500015
India

Central giant cell granuloma (CGCG) is an uncommon, benign but aggressive osteolytic neoplasm of the craniomaxillofacial region, histologically characterized by an abundance of evenly distributed multinucleated giant cells within a sea of spindle-shaped mesenchymal stromal cells, scattered throughout the fibrovascular connective tissue stroma containing areas of hemorrhage. A rapid diagnostic assessment, together with an adequate histopathologic verification, is essential to improve the management and the prognosis of this locally destructive lesion. A rare case of a large destructive CGCG involving the entire right angle of mandible, causing extensive bony resorption, and buccal, medial as well as inferior border cortical expansion with multiple perforations, in a young child is presented. It was treated successfully by enucleation and aggressive curettage followed by peripheral ostectomy preserving the continuity of the mandible. Two adjunctive measures were employed; first, chemical cauterization of the residual bony walls to prevent possible recurrence, for which this tumor is notorious, and second, placement of fresh autologous platelet-rich fibrin within the bony defect to hasten bone fill and reossification, thus obviating the need for a bone graft.


How to cite this article:
Jeyaraj P. Management of central giant cell granulomas of the jaws: An unusual case report with critical appraisal of existing literature.Ann Maxillofac Surg 2019;9:37-47


How to cite this URL:
Jeyaraj P. Management of central giant cell granulomas of the jaws: An unusual case report with critical appraisal of existing literature. Ann Maxillofac Surg [serial online] 2019 [cited 2019 Dec 11 ];9:37-47
Available from: http://www.amsjournal.com/article.asp?issn=2231-0746;year=2019;volume=9;issue=1;spage=37;epage=47;aulast=Jeyaraj;type=0