Home  -  About us  -  Editorial board  -  Search  -  Ahead of print  -  Current issue  -  Archives  -  Instructions  -  Subscribe  -  Contacts  -  Advertise - Login 
 
 
     

 Table of Contents  
EDITORIAL
Year : 2014  |  Volume : 4  |  Issue : 2  |  Page : 127

Craniofacial reconstruction and stem cell engineering


Director and Consultant Maxillofacial Surgeon, Balaji Dental and Craniofacial Hospital, 30, KB Dasan Road, Teynampet, Chennai - 600 018, Tamil Nadu, India

Date of Web Publication16-Dec-2014

Correspondence Address:
S M Balaji
Director and Consultant Maxillofacial Surgeon, Balaji Dental and Craniofacial Hospital, 30, KB Dasan Road, Teynampet, Chennai - 600 018, Tamil Nadu
India
Login to access the Email id


DOI: 10.4103/2231-0746.147084

Rights and Permissions

How to cite this article:
Balaji S M. Craniofacial reconstruction and stem cell engineering. Ann Maxillofac Surg 2014;4:127

How to cite this URL:
Balaji S M. Craniofacial reconstruction and stem cell engineering. Ann Maxillofac Surg [serial online] 2014 [cited 2021 Apr 18];4:127. Available from: https://www.amsjournal.com/text.asp?2014/4/2/127/147084

The birth of 21 st century heralded many advances in the craniofacial reconstruction arena. Many basic works, that was initiated in the mid of 20 th century started to get translated to clinical works. This witnessed birth of newer, rapid methods of craniofacial reconstruction. At the same time, even facial transplants became a reality. Such was the rapid advancement of science.

With the emergence of adipocyte and osteosynthesis technique, [1] more opportunities began to emerge. These cells which have been dreaded by the young adults, partly in the form of cellulite, began to emerge as a wholesome, simple treatment option. Several pioneers began using this option to reconstruct craniofacial bones [2],[3] successfully. With these huge success stories, the hunt for bringing this technology has already begun. As the cells can be successfully harvested from self, there is no risk of allergic or immunologic reaction. Besides the stem cells being a part of the host, an inflammatory reaction would be lowest. In addition, there are few or no risks of adverse reactions. The long-term effect of such regenerative procedures is still not known. However considering the huge benefits coming out of this technique, expansion of the adipocyte stem cell for craniofacial reconstruction is need of the hour. Though, the initial expense for installing the infrastructure is high, the long-term savings in terms of man hours, additional materials, drugs, etc., would be extremely beneficial. Furthermore, when translated to bedside procedure in several centers, the cost of the infrastructure and consumables would further drop. Hope the technique would rapidly be incorporated into regular clinical oral and maxillofacial surgery practice.

 
  References Top

1.
Hicok KC, Du Laney TV, Zhou YS, Halvorsen YD, Hitt DC, Cooper LF, et al. Human adipose-derived adult stem cells produce osteoid in vivo. Tissue Eng 2004;10:371-80.  Back to cited text no. 1
    
2.
Sándor GK. Tissue engineering of bone: Clinical observations with adipose-derived stem cells, resorbable scaffolds, and growth factors. Ann Maxillofac Surg 2012;2:8-11.  Back to cited text no. 2
    
3.
Wolff J, Sándor GK, Miettinen A, Tuovinen VJ, Mannerström B, Patrikoski M, et al. GMP-level adipose stem cells combined with computer-aided manufacturing to reconstruct mandibular ameloblastoma resection defects: Experience with three cases. Ann Maxillofac Surg 2013;3:114-25.  Back to cited text no. 3
[PUBMED]  Medknow Journal  



This article has been cited by
1 The Role of Skeletal Stem Cells in the Reconstruction of Bone Defects
Matthew P. Murphy,Dre Irizarry,Michael Lopez,Alessandra L. Moore,Ryan C. Ransom,Michael T. Longaker,Derek C. Wan,Charles K.F. Chan
Journal of Craniofacial Surgery. 2017; 28(5): 1136
[Pubmed] | [DOI]



 

Top
 
 
Search
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)  

 
  In this article
   References

 Article Access Statistics
    Viewed1894    
    Printed71    
    Emailed0    
    PDF Downloaded2243    
    Comments [Add]    
    Cited by others 1    

Recommend this journal