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 Table of Contents  
Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 434-438

Mandibular condyle osteoma

Department of Cranio-Maxillofacial Surgery, Unit of Cranio-Maxillofacial Surgery, University Hospital of Ferrara, Ferrara, Italy

Date of Web Publication11-Dec-2019

Correspondence Address:
Luisa Valente
University Hospital of Ferrara, Via Aldo Moro 8, 44122, Ferrara
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DOI: 10.4103/ams.ams_174_19

PMID: 31909031

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Background: Osteoma is a benign tumor composed of both cortical and cancellous bones that increase in size with continuous formation of bone. The pathogenesis is unknown. Osteomas can cause symptoms depending on their location and size. They can be asymptomatic or symptomatic, with trismus, limitation of mouth opening, and progressive malocclusion with facial asymmetry and can be painful. Aim: The aim of this paper is to report an unusual case of osteoma in the mandibular condylar neck and review the cases of mandibular condyle osteomas that have been reported in the last 15 years. Conclusions: Only a few cases involving the temporomandibular joint have been reported. We report an unusual case of osteoma in the mandibular condylar neck causing restricted mouth opening in addition to pain. Complete surgical excision in symptomatic cases is the therapy of choice with a low recurrence rate.

Keywords: Condyle, facial asymmetry, mandible, osteogenic tumor, osteoma, temporomandibular joint

How to cite this article:
Valente L, Tieghi R, Mandrioli S, Galiè M. Mandibular condyle osteoma. Ann Maxillofac Surg 2019;9:434-8

How to cite this URL:
Valente L, Tieghi R, Mandrioli S, Galiè M. Mandibular condyle osteoma. Ann Maxillofac Surg [serial online] 2019 [cited 2021 Aug 5];9:434-8. Available from: https://www.amsjournal.com/text.asp?2019/9/2/434/272583

  Introduction Top

Osteoma is a benign tumor composed of both cortical and cancellous bones that increase in size with continuous formation of bone.[1] It represents an uncommon lesion that occurs mainly in craniofacial complex bones.[2] In jaws, it can appear on the bone surface as a polypoid or sessile mass, characterizing a peripheral osteoma, or can be a lesion in the medullar space, called central osteoma.[3] The majority of osteomas in the craniofacial skeleton are peripheral, while central osteomas are uncommon.[4]

The pathogenesis is unknown. Reaction mechanisms, traumas, or infections are suggested as possible causes.[5] They affect most young adults, with no preference by sex. The mandibular cases occur in the angle, mandibular condyle, and molar regions of the body, being frequent intraoral cases in the lingual regions close to molars and premolars.[6] When the mandibular condyle is involved, trismus, limitation of mouth opening, progressive malocclusion with midline shift toward the nonaffected side, contralateral mandibular deviation, and facial asymmetry are the common findings.[3],[6]

In Gardner syndrome, multiple maxillary osteomas can be associated with multiple intestinal polyposes, osteomas, and epidermoid cysts. In addition, dental abnormalities include an increased frequency of multiple odontomas, as well as supernumerary and impacted teeth.[7]

We report an unusual case of osteoma in the mandibular condylar neck that presented in a 52-year-old female, causing restricted mouth opening in addition to pain.

  Case Report Top

A 52-year-old female presented to the outpatient clinic of the Craniomaxillofacial Surgery Unit of the University of Ferrara (Italy) with a 7-year history of a slow-growing swelling over the preauricular area and pain of the temporomandibular joint (TMJ) area radiating to the right face.

The onset of the swelling was insidious and gradually increasing in size. It was not associated with trauma or infection and the patient had not undergone any recent surgery.

On physical examination, there was pain in the right TMJ during mouth opening and palpation. Maximum mouth opening was limited to 1.2 cm [Figure 1]. There was malocclusion with mandibular deviation toward the right side on mouth opening and limitation of lateral and protrusion movements. On palpation, there was a swelling in the right preauricular region. The swelling was bony hard in consistency and nontender and attached to the underlying bone. The overlying skin was normal and freely movable, and there was no local rise in temperature. No regional lymph nodes were palpable.
Figure 1: Preoperative mouth opening 12 mm

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Computed tomography (CT) scan showed a well-defined radiopaque lesion involving the glenoid fossa and the right condyle [Figure 2]a and [Figure 2]b. Routine hematological and biochemical investigations were within the normal limits.
Figure 2: (a) Preoperative computed tomography scan coronal view. (b) Preoperative computed tomography scan axial view

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Surgical correction was planned and performed under general anesthesia. The lesion was approached through a preauricular incision with temporal extension. After exposure of the entire lesion, an osteotomy was made with piezosurgery so that the condyle head with the lesion could be removed. A pedicled temporalis muscle flap was raised and positioned in the glenoid cavity, as interpositional material between the bony articular surfaces.

An intraoral incision was made and the right coronoid process was approached with stripping of the temporalis attachment on the anterior border of ramus. An osteotomy cut from the sigmoid notch to the anterior border of ramus was done, and the coronoidectomy was performed.

After the procedure, the maximum mouth opening was 5 cm. A subcutaneous suction drain was inserted. Sutures and dressing completed the operation. The specimen was sent for histopathological examination, which confirmed osteoma. The recovery was uneventful.

A 6-month postoperative CT scan showed a stable morphological result [Figure 3]a and [Figure 3]b.
Figure 3: (a) Postoperative computed tomography scan coronal view. (b) Postoperative computed tomography scan axial view

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At 12-month follow-up, the patient showed an improvement in facial symmetry with a good mouth opening (32 mm) [Figure 4]a and [Figure 4]b and stable occlusion and with no limitations in mandibular movements or pain in mouth opening. No signs of recurrence were observed.
Figure 4: (a) Twelve-month postoperative follow-up. Mouth opening 32 mm. (b) Close-up of mouth opening

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  Discussion Top

Osteomas of the mandibular condyle are considered extremely infrequent lesions. The first case of a condylar osteoma was described in 1927 by Ivy.[8] Since then, only few cases of osteoma arising from the condylar process have been reported. The pathogenesis is unknown. Some authors consider osteoma true neoplasia, while others consider it a hamartoma. The precise location of an osteoma is usually in proximity to the regions of muscle attachment, suggesting that muscle traction may play a role in its development.[9] Reaction mechanisms, traumas, or infections are also suggested as possible etiologic factors.[5]

In jaws, osteomas may appear on the surface of the bone as a polypoidal or sessile mass, arising from the cortical bone (peripheral osteoma), or can be located within the medullary space, arising from cancellous bone (central osteoma). Thus, osteomas occurring in the mandibular condyle can appear as a sessile or pedunculated mass on the condylar head or neck (peripheral osteoma) or proliferate and replace the condyle (central osteoma).

Osteomas can cause symptoms depending on their location and size. They can be asymptomatic if the lesions tend to be small, solitary, slow-growing, and painless, and in these cases, they are only noticeable during routine examinations.[6] As these lesions have a progressive growth, they can cause trismus, limitation of mouth opening, progressive malocclusion with midline shift toward the nonaffected side, contralateral mandibular deviation, and facial asymmetry and be painful.

In the last 15 years, only nine cases of mandibular condyle osteoma have been documented in the literature [Table 1]. PubMed and Cochrane Library were used as a source of research.
Table 1: Cases of mandibular condyle osteoma documented in the last 15 years

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By analyzing the reported cases, we inferred that the majority of osteoma cases involving the mandibular condyle occurred during the fourth and fifth decades of life (mean age 42.8 years), with a slight female predilection (female-to-male ratio 1.25:1).

Facial asymmetry, malocclusion, and limited mouth opening were the most common clinical findings.

Surgical intervention with removal of the lesion was the preferred treatment.

Radiographically, osteomas appear as circumscribed masses similar in density to normal bone. At their centers, these masses may exhibit a mixed radiolucent-radiopaque appearance, depending on the number of marrow tissues present. Small endosteal osteomas are difficult to differentiate from foci of condensing osteitis, focal chronic sclerosing osteomyelitis, or idiopathic osteosclerosis.[2] Radiographic images, such as panoramic radiographs, CT, magnetic resonance imaging, and scintigraphy, are utilized for diagnosis. CT scan with three-dimensional reconstruction is the most useful in locating the lesion, showing more details about the relationship between the osteoma and the adjacent structures. Activity in the lesion is diagnosed by scintigraphy.[15]

Histologically, osteoma is reported as either a normal-appearing dense mass of lamellar bone with minimal marrow tissues (compact osteoma) or trabeculae of mature lamellar bone, with intervening fatty or fibrous marrow (cancellous osteoma).[16]

There are no reports of osteomas undergoing malignant transformation.[9]

Patients with osteomas should be evaluated for Gardner syndrome,[9] which is defined as multiple osteomas of the jaws accompanied by colorectal polyposis with high malignant potentials,[16] anomalies involving soft and hard tissues, congenital retinal pigment hypertrophies, multiple impacted or supernumerary teeth, desmoids tumors, and epidermoid cysts. These patients may present with symptoms of rectal bleeding, diarrhea, and abdominal pain. The triad of colorectal polyposis, skeletal abnormalities, and multiple impacted or supernumerary teeth is consistent with this syndrome. Onset occurs at an average age of 16 years, with malignant transformation of the colorectal polyps approaching 100% by age 40.[9],[17]

Differential diagnosis should include maxillary or mandibular exostoses, osteoid osteoma, and osteoblastoma. Exostoses are bony excrescences that occur on the buccal aspect of alveolar bone. These lesions are of reactive or developmental origin and are not thought to be true neoplasms. Osteoblastoma and osteoid osteomas are more frequently painful and may exhibit a more rapid rate of growth than osteomas.[9]

The treatment of this pathology is determined according to the clinical and radiological examination, the extension of the lesion, and the possible complications for the patient.

In general, symptomless osteomas do not necessarily require treatment. However, when symptoms such as functional disorders (limitation of mouth opening, malocclusion, and mandibular deviation) facial asymmetry and pain are also present, surgical treatment is indicated.[11],[18],[19],[20],[21]

The optimal treatment for osteomas consists of complete surgical removal at the base where it unites with the cortical bone,[9] without compromising the adjacent structures.

Reconstruction of TMJ is a complex surgical procedure, and it entails improved mandibular form and function and reduction of pain and disability.[6]

Total TMJ replacement using alloplastic prosthesis may provide satisfactory results in cases of functional alterations of the TMJ due to the presence of tumors with irreversible joint damage.[6]

For the treatment of this case, we preferred surgical excision, with a conservative removal of the lesion, TMJ arthroplasty, and TMF interposition.

In the present case, resection of the right mandibular condyle osteoma resulted in the restoration of facial symmetry and a greatly improved molar occlusal relationship. The results were stable at 12-month follow-up.

  Conclusions Top

Osteomas of the mandibular condyle are considered extremely infrequent lesions.

CT scan is the examination of choice for surgical planning purposes. The treatment of this pathology will be determined according to the clinical and radiological examination, the extension of the lesion, and the possible complications for the patient.

Symptomless osteomas do not necessarily require treatment. When symptoms such as functional disorders, facial asymmetry, and pain are present, surgical treatment is indicated. Surgery with complete lesion excision is the most adequate treatment, with low recurrence rates.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Yonezu H, Wakoh M, Otonari T, Sano T, Hashimoto S, Uchiyama T. Osteoma of mandibular condyle as cause of acute pain and limited-mouth-opening: Case report. Bull Tokyo Dent Coll 2007;48:193-7.  Back to cited text no. 1
Siar CH, Jalil AA, Ram S, Ng KH. Osteoma of the condyle as the cause of limited-mouth opening: A case report. J Oral Sci 2004;46:51-3.  Back to cited text no. 2
Almeida LE, de Oliveira Filho MA. Giant mandibular condyle osteoma. J Craniofac Surg 2011;22:1147-9.  Back to cited text no. 3
Larrea-Oyarbide N, Valmaseda-Castellón E, Berini-Aytés L, Gay-Escoda C. Osteomas of the craniofacial region. Review of 106 cases. J Oral Pathol Med 2008;37:38-42.  Back to cited text no. 4
Horikawa FK, Freitas RR, Maciel FA, Gonçalves AJ. Peripheral osteoma of the maxillofacial region: A study of 10 cases. Braz J Otorhinolaryngol 2012;78:38-43.  Back to cited text no. 5
de Souza NT, Cavalcante RC, de Albuquerque Cavalcante MA, Hespanhol W, de Oliveira MR Jr., de Carvalho Ferreira D, et al. An unusual osteoma in the mandibular condyle and the successful replacement of the temporomandibular joint with a custom-made prosthesis: A case report. BMC Res Notes 2017;10:727.  Back to cited text no. 6
Koh KJ, Park HN, Kim KA. Gardner syndrome associated with multiple osteomas, intestinal polyposis, and epidermoid cysts. Imaging Sci Dent 2016;46:267-72.  Back to cited text no. 7
Ivy RH. Benign bony enlargement of the condyloid process of the mandible. Ann Surg 1927;85:27-30.  Back to cited text no. 8
Sayan NB, Uçok C, Karasu HA, Günhan O. Peripheral osteoma of the oral and maxillofacial region: A study of 35 new cases. J Oral Maxillofac Surg 2002;60:1299-301.  Back to cited text no. 9
Heitz C, Conci RA, Tomazi FH, Louzada GP, Guarenti MM, Fritscher GG. Giant peripheral temporomandibular osteoma with immediate reconstruction of mandible. J Craniofac Surg 2018;29:e146-9.  Back to cited text no. 10
Nojima K, Niizuma-Kosaka F, Nishii Y, Sueishi K, Yamakura D, Ikumoto H, et al. Multidisciplinary treatment of peripheral osteoma arising from mandibular condyle in patient presenting with facial asymmetry. Bull Tokyo Dent Coll 2014;55:39-47.  Back to cited text no. 11
Cogburn AC, Hales N, Krempl GA. Endoscopic resection of a mandibular condyle osteoma: Report of a case. Laryngoscope 2008;118:1214-6.  Back to cited text no. 12
Ortakoǧlu K, Gunaydin Y, Aydintug YS, Safali M. Osteoma of the mandibular condyle: Report of a case with 5-year follow-up. Mil Med 2005;170:117-20.  Back to cited text no. 13
Mancini JC, Woltmann M, Felix VB, Freitas RR. Peripheral osteoma of the mandibular condyle. Int J Oral Maxillofac Surg 2005;34:92-3.  Back to cited text no. 14
Misra N, Srivastava S, Bodade PR, Rastogi V. Osteoma of temporomandibular joint: A rarity. BMJ Case Rep 2013;2013. pii: bcr2013200268.  Back to cited text no. 15
Zafar E, Akbar Z, Niazi K, Pasha B. Osteoma of mandubular condyle – A case report. Pak Oral Dent J 2016;36:383-6.  Back to cited text no. 16
Jasperson KW, Patel SG, Ahnen DJ. APC-Associated Polyposis Conditions. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. GeneReviews ® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019; 1998. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1345/. [Last updated on 2017 Feb 02].  Back to cited text no. 17
Galiè M, Consorti G, Tieghi R, Denes SA, Fainardi E, Schmid JL, et al. Early surgical treatment in unilateral coronoid hyperplasia and facial asymmetry. J Craniofac Surg 2010;21:129-33.  Back to cited text no. 18
Aimoni C, Ciorba A, Cappiello L, Giuriato R, Denes SA, Galiè M. Pigmented villonodular synovitis of the temporomandibular joint. J Craniofac Surg 2012;23:e168-70.  Back to cited text no. 19
Clauser LC, Consorti G, Elia G, Tieghi R, Galiè M. Management of temporomandibular joint reankylosis in syndromic patients corrected with joint prostheses: Surgical and rehabilitation protocols. Craniomaxillofac Trauma Reconstr 2014;7:71-8.  Back to cited text no. 20
Tieghi R, Galiè M, Piersanti L, Clauser L. Bilateral hyperplasia of the coronoid processes: Clinical report. J Craniofac Surg 2005;16:723-6.  Back to cited text no. 21


  [Figure 1], [Figure 2], [Figure 3], [Figure 4]

  [Table 1]

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